In CRAWLERS, a catastrophic infestation of venomous and deadly spiders sends an apartment building into lockdown. Trapped inside by a police-mandated quarantine, building manager Serena (Matilda Lutz) and her residents battle to survive as the creatures multiply by the second. Armed with her intimate knowledge of the complex, Serena may be the only one who can keep them alive—if she can confront her deepest fear.